fbpx
All Posts By

tmilligan

EXAKT Results

Compounding EXAKT

EXAKT three ointment mills deliver results that are consistent and reproducible.

A comparative study conducted at the University of Hamburg, Institute of Pharmacy in Hamburg, Germany concluded that the quality of ointments processed with three roll mills is better than those processed with electric mixing systems. The study highlighted the following conclusions:

  • The particle size is smaller.
  • Particle size distribution is narrow.
  • Ointment stability is better.
  • Temperatures do not increase significantly during processing.
  • Ointments are softer consistency with lower flow limits.
  • Ointment mills allow for quality control during processing.

Ointment Mill Advantages

Three roll mill advantages

Only the ointment mill used in the dispersing process guarantees that 100% of the product will be passed through both shear zones.

  • The shear rate between the rollers is the decisive factor for the process.
  • This is determined by the roller spacing and the circumferential speed.
  • Agglomerates and powder clumps are broken up and homogenized.
  • The more controlled the energy input, the more precise the processing.

Introducing a New and Smaller Pathology Saw

SMALLER FOOTPRINT, LOWER PRICEEXAKT 302

Designed for tight spaces and tight budgets, this new saw is perfect for any pathology lab. The new 302 is a smaller version of the EXAKT 312 Pathology Saw. The new 302 fits perfectly on standard laboratory tabletops.
  • Minimize your risk of injury with a saw designed for the pathology laboratory.
  • Gross hard or soft tissue quickly and safely down to 1 mm.
  • Our exclusive diamond band moves through screws and metal implants effortlessly.
  • You’ll dramatically reduce processing time for sample preparation.
  • Water circulation is excellent for cooling and bone dust reduction.
  • Made of high-grade stainless steel.
  • UL and CSA certified

 

Request Info

Five Reasons To Choose the 302

Elegant Ointments

EXAKT ointment mills produced ointments with softer consistency and lower flow limits than those produced with EMPs, most likely due to the significant temperature increase of ointments processed with EMPs (electronic mortar & pestle).

What does an ointment mill do?

Three Roll Mill Process

An ointment mill utilizes high shear force to disperse active ingredients, and homogenize viscous materials.

Shear force is created by three horizontally positioned rollers rotating in opposite directions and at different speeds relative to each other.

The product is pulled through the gaps between the rollers. Active ingredients and powder clumps are broken up and homogenized, which removes grittiness and results in a high-quality topical.  This gives your customers a pharmaceutically elegant and effective ointment.

 

 

 

The EXAKT 120EH-450 Three Roll Mill

The EXAKT 120EH-450 is the highest performance three roll mill of the E-Line series. Developed for production, the mill offers options for the automatic filling, monitoring, and cooling. The electronic control concept enables the precise setting of all relevant processing parameters. Recurrent production processes can also be programmed and all operating parameters continuously stored. This means they are available at any time for documentation or for subsequent analysis of the results. Reproducible, consistent and documented quality is the precondition for efficient production.

  • Achievable fineness of less than 1 μm
  • Gap or power mode optionally selectable per gap
  • One-pass calibration – automatic adjustment of the spacing and parallelism of the rollers
  • Electronic display of all operating parameters
  • DataLog – documentation of processing parameters
  • Throughput up to 14 or 27.5 l/h with a gap width of 5 μm
  • Roller temperature control for optimum process control
  • Safe working – overload protection, cleaning and reverse mode
  • Scale-up from the laboratory to production