In a compounding pharmacy, achieving a smooth, uniform ointment with optimal particle size and consistency is critical for efficacy and patient satisfaction. While traditional electric mixers are common, they often fall short when precision and quality matter most.
EXAKT ointment mills deliver superior results backed by scientific evidence and real-world performance advantages. A comparative study from the University of Hamburg’s Institute of Pharmacy found that ointments processed with EXAKT mills significantly outperform those mixed with conventional electric systems in key quality metrics.
1. Finer, More Uniform Particle Size
One of the primary benefits of EXAKT ointment mills is their ability to produce smaller and more narrowly distributed particles compared with conventional mixers. Because material is sheared between three precisely controlled rollers, agglomerates are broken down more thoroughly, resulting in enhanced dispersion and a smoother product.
2. Enhanced Ointment Stability
Stability is essential for compounding formulations, especially those containing active pharmaceutical ingredients (APIs). The milling action of EXAKT mills improves the homogeneity of the formulation, leading to better stability over time—a factor that can improve performance and shelf life.
3. Controlled Temperature During Processing
Temperature control is a major challenge in high-viscosity mixing. Excess heat can degrade heat-sensitive ingredients and alter rheological properties. EXAKT’s 80E Plus and 120EH models can minimize temperature rise because the material is processed between cooled rollers, reducing the risk of thermal degradation.
4. Softer, More Consistent Flow Properties
Products processed on EXAKT mills often demonstrate softer consistency with lower flow limits. This translates to better spreadability and texture, especially for topical applications, lotions, and high-viscosity creams. Such rheological improvements are critical in compounding pharmacies where customization and performance are paramount.
5. Real-Time Quality Control During Milling
Unlike traditional mixing systems, where dispersion quality can only be evaluated after processing, three roll milling enables visual monitoring of the process. Pharmacies can adjust parameters like roller gap and speed in real time to optimize results, ensuring consistent quality from batch to batch.
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Ready to elevate your compounding outcomes? Contact one of our distributors for the 50 Plus Pharma.
For larger mills, contact EXAKT directly to request a quote or arrange a demonstration.
