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Ointment Mills for Pharmacy

Conventional Mixing vs. EXAKT Milling

Compounding EXAKT

A comparative study conducted at the University of Hamburg, Institute of Pharmacy in Hamburg Germany concluded that the quality of compounds processed with three roll mills is better than those processed with electric mixing systems.

  • Particle size is smaller.
  • Particle size distribution is narrow.
  • Ointment stability is better.
  • Temperatures do not increase significantly during processing.
  • Ointments are softer consistency with lower flow limits
  • Three roll mills allow for quality control during processing.

 

Substance processed with conventional mixing procedure: crystalline substances are still clearly visible.

Substance processed with an EXAKT three roll mill: regular and fine consistency of the substance

EXAKT Results

EXAKT three ointment mills deliver results that are consistent and reproducible.

A comparative study conducted at the University of Hamburg, Institute of Pharmacy in Hamburg, Germany concluded that the quality of ointments processed with three roll mills is better than those processed with electric mixing systems. The study highlighted the following conclusions:

  • The particle size is smaller.
  • Particle size distribution is narrow.
  • Ointment stability is better.
  • Temperatures do not increase significantly during processing.
  • Ointments are softer consistency with lower flow limits.
  • Ointment mills allow for quality control during processing.

Ointment Mill Advantages

Three roll mill advantages

Only the ointment mill used in the dispersing process guarantees that 100% of the product will be passed through both shear zones.

  • The shear rate between the rollers is the decisive factor for the process.
  • This is determined by the roller spacing and the circumferential speed.
  • Agglomerates and powder clumps are broken up and homogenized.
  • The more controlled the energy input, the more precise the processing.

Elegant Ointments

Compounding EXAKT

EXAKT ointment mills produced ointments with softer consistency and lower flow limits than those produced with EMPs, most likely due to the significant temperature increase of ointments processed with EMPs (electronic mortar & pestle).

What does an ointment mill do?

An ointment mill utilizes high shear force to disperse active ingredients, and homogenize viscous materials.

Shear force is created by three horizontally positioned rollers rotating in opposite directions and at different speeds relative to each other.

The product is pulled through the gaps between the rollers. Active ingredients and powder clumps are broken up and homogenized, which removes grittiness and results in a high-quality topical.  This gives your customers a pharmaceutically elegant and effective ointment.

 

 

 

Why Choose EXAKT Ointment Mills

Because precision matters.

Experience – More than 60 years in milling compounds, more than 45,000 systems installed worldwide.

Expertise – Extensive knowledge of applications with a wide variety of materials.

Service – Factory-trained technicians are available to help repair and extend the life of your equipment.

Products – Machines are made for the customer with the highest precision in manufacturing and assembly. And we have the smallest tolerance ranges in the market.

Precision – Nothing says precision and quality like German engineering.

The EXAKT 120S-450 Three Roll Mill

The EXAT 120S-450 offers continuously good results at particle fineness down to 5 μm. When increased volume and simple handling are required, the120S-450 is the best choice. The process conditions are very easily adapted to the product to be processed. A continuously adjustable processing speed, excellent temperature control, and alternative roller materials provide the best prerequisites for a multitude of material requirements. The compact desktop model is found everywhere in production. The solid processing of the machine provides absolutely parallel, manually adjusted roller gaps for uniform processing.

EXAKT 120S-450 - Pharmacy Mills

 

  • Roller gap to 5 μm
  • Precise setting of the roller gap, no dry running possible
  • Up to 27.5 l/h throughput with a gap width of 5 μm
  • Digitally adjustable circumferential speed of the rollers
  • Ceramic (aluminum oxide, silicon carbide) or hardened chrome rollers
  • Precise one-hand adjustment, continuous and with scale
  • High safety standard