fbpx
Tag

dispersion | Exakt Technologies

EXAKT Results

Compounding EXAKT

EXAKT three ointment mills deliver results that are consistent and reproducible.

A comparative study conducted at the University of Hamburg, Institute of Pharmacy in Hamburg, Germany concluded that the quality of ointments processed with three roll mills is better than those processed with electric mixing systems. The study highlighted the following conclusions:

  • The particle size is smaller.
  • Particle size distribution is narrow.
  • Ointment stability is better.
  • Temperatures do not increase significantly during processing.
  • Ointments are softer consistency with lower flow limits.
  • Ointment mills allow for quality control during processing.

What does an ointment mill do?

Three Roll Mill Process

An ointment mill utilizes high shear force to disperse active ingredients, and homogenize viscous materials.

Shear force is created by three horizontally positioned rollers rotating in opposite directions and at different speeds relative to each other.

The product is pulled through the gaps between the rollers. Active ingredients and powder clumps are broken up and homogenized, which removes grittiness and results in a high-quality topical.  This gives your customers a pharmaceutically elegant and effective ointment.

 

 

 

The EXAKT 120EH-450 Three Roll Mill

The EXAKT 120EH-450 is the highest performance three roll mill of the E-Line series. Developed for production, the mill offers options for the automatic filling, monitoring, and cooling. The electronic control concept enables the precise setting of all relevant processing parameters. Recurrent production processes can also be programmed and all operating parameters continuously stored. This means they are available at any time for documentation or for subsequent analysis of the results. Reproducible, consistent and documented quality is the precondition for efficient production.

  • Achievable fineness of less than 1 μm
  • Gap or power mode optionally selectable per gap
  • One-pass calibration – automatic adjustment of the spacing and parallelism of the rollers
  • Electronic display of all operating parameters
  • DataLog – documentation of processing parameters
  • Throughput up to 14 or 27.5 l/h with a gap width of 5 μm
  • Roller temperature control for optimum process control
  • Safe working – overload protection, cleaning and reverse mode
  • Scale-up from the laboratory to production

Why Choose EXAKT Ointment Mills

Compounding EXAKT

Because precision matters.

Experience – More than 60 years in milling compounds, more than 45,000 systems installed worldwide.

Expertise – Extensive knowledge of applications with a wide variety of materials.

Service – Factory-trained technicians are available to help repair and extend the life of your equipment.

Products – Machines are made for the customer with the highest precision in manufacturing and assembly. And we have the smallest tolerance ranges in the market.

Precision – Nothing says precision and quality like German engineering.

The EXAKT 120EH-250 Three Roll Mill

The EXAKT 120E provides higher productivity and more power with the same precision as the 80E Plus. This makes it the ideal equipment for a scale-up when higher production volumes are required. Continuously excellent results for particle fineness down to 1 μm and stable production conditions. This mill has proven its worth wherever maximum reproducibility and control are required. This model is found in laboratory and production environments.

  • Achievable fineness of less than 1 μm
  • Gap or power mode optionally selectable per gap
  • One-pass calibration – automatic adjustment of the spacing and parallelism of the rollers
  • Electronic display of all operating parameters
  • DataLog – documentation of processing parameters
  • Throughput up to 14 l/h with a gap width of 5 μm
  • Roller temperature control for optimum process control
  • Safe working – overload protection, cleaning, and reverse mode
  • Scraper knife angle adjustable

The EXAKT 120S-450 Three Roll Mill

The EXAT 120S-450 offers continuously good results at particle fineness down to 5 μm. When increased volume and simple handling are required, the120S-450 is the best choice. The process conditions are very easily adapted to the product to be processed. A continuously adjustable processing speed, excellent temperature control, and alternative roller materials provide the best prerequisites for a multitude of material requirements. The compact desktop model is found everywhere in production. The solid processing of the machine provides absolutely parallel, manually adjusted roller gaps for uniform processing.

EXAKT 120S-450 - Pharmacy Mills

 

  • Roller gap to 5 μm
  • Precise setting of the roller gap, no dry running possible
  • Up to 27.5 l/h throughput with a gap width of 5 μm
  • Digitally adjustable circumferential speed of the rollers
  • Ceramic (aluminum oxide, silicon carbide) or hardened chrome rollers
  • Precise one-hand adjustment, continuous and with scale
  • High safety standard

The EXAKT 80E Plus Three Roll Mill

The 80E PLUS three roll mill delivers faster-dispersing results with real-time process analysis. By combining high-precision mechanical design with a state-of-the-art electronic control system, EXAKT has created the new standard for three roll mill technology.

Users will have more information than ever before, and the ability to make adjustments on the go.

  • Safe operation mode for the cleaning process
  • Numeric or graphical real-time presentation of all relevant production parameters
  • Easy to use data transfer via USB interface
  • Gap Mode: Adjustable gap size from 5 to 180 μm
  • Force Mode: Line pressure adjustable up to max. 26 N/mm, depending on working width
  • Variable throughput from as little as 10 ml up to 18 l/h at a 10 μm gap
  • Roller materials chrome, tungsten carbide, aluminum oxide or silicon carbide

The EXAKT 80E Plus Three Roll Mill

The 80E PLUS three roll mill delivers faster-dispersing results with real-time process analysis. By combining high-precision mechanical design with a state-of-the-art electronic control system, EXAKT has created the new standard for three roll mill technology.

Users will have more information than ever before, and the ability to make adjustments on the go.

  • Safe operation mode for the cleaning process
  • Numeric or graphical real-time presentation of all relevant production parameters
  • Easy to use data transfer via USB interface
  • Gap Mode: Adjustable gap size from 5 to 180 μm
  • Force Mode: Line pressure adjustable up to max. 26 N/mm, depending on working width
  • Variable throughput from as little as 10 ml up to 18 l/h at a 10 μm gap
  • Roller materials chrome, tungsten carbide, aluminum oxide or silicon carbide

The EXAKT 120S-450 Three Roll Mill

The latest generation of the EXAK T 120S Plus Three Roll Mill technology features state-of-the-art safety functionality, optimum operation and precise setting of the gap.

The EXAT 120S Plus offers continuously good results at particle fineness down to 5 μm. When the increased volume and simple handling are required, the120S-450 is the best choice. The process conditions are very easily adapted to the product to be processed. A continuously adjustable processing speed, excellent temperature control, and alternative roller materials provide the best prerequisites for a multitude of material requirements. The compact desktop model is found everywhere in production. The solid processing of the machine provides absolutely parallel, manually adjusted roller gaps for uniform processing.

 

EXAKT 120S Plus

  • Easily monitor speed, temperature, production timer, and power consumption
    on the color display
  • Roller gap to 5 μm
  • Precise setting of the roller gap, no dry running possible
  • Up to 27 l/h throughput with a gap width of 10 μm
  • Ceramic (aluminum oxide, silicon carbide) or hardened chrome rollers
  • Precise one-hand adjustment, continuous and with scale
  • High safety standard
  • Separate cleaning and reverse operation mode