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dispersion | Exakt Technologies

Conventional Mixing vs EXAKT Milling

EXAKT Ointment Mill Results

A study at the University of Hamburg, Institute of Pharmacy in Hamburg Germany concluded that the quality of compounds processed with three roll mills is better than those processed with electric mixing systems.

  • The particle size is smaller and the distribution is more narrow.
  • Ointment stability is better.
  • Temperatures do not increase significantly during processing.
  • Ointments are softer consistency with lower flow limits
  • Three roll mills allow for quality control during processing.

Substance processed with conventional mixing procedure: crystalline substances are still clearly visible.

Substance processed with an EXAKT three roll mill: regular and fine consistency of the substance

What does an ointment mill do?

EXAKT-80E-Plus-with-Hopper

An ointment mill utilizes high shear force to disperse active ingredients, and homogenize viscous materials. Shear force is created by three horizontally positioned rollers rotating in opposite directions and at different speeds relative to each other.

The product is pulled through the gaps between the rollers. Active ingredients and powder clumps are broken up and homogenized, which removes grittiness and results in a high-quality topical.  This gives your customers a pharmaceutically elegant and effective ointment.

Learn more.

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7 Reasons to Choose the EXAKT 80E Plus Three Roll Mill

EXAKT80E Pus Hopper

The 80E PLUS three roll mill delivers faster-dispersing results with real-time process analysis. By combining high-precision mechanical design with a state-of-the-art electronic control system, EXAKT has created the new standard for three roll mill technology.

Users will have more information than ever before, and the ability to make adjustments on the go.

  1. Safe operation mode for the cleaning process
  2. Numeric or graphical real-time presentation of all relevant production parameters
  3. Easy to use data transfer via USB interface
  4. Gap Mode: Adjustable gap size from 5 to 180 μm
  5. Force Mode: Line pressure adjustable up to max. 26 N/mm, depending on the working width
  6. Variable throughput from as little as 10 ml up to 18 l/h at a 10 μm gap
  7. Roller materials chrome, tungsten carbide, aluminum oxide, or silicon carbide

Request quote.

Conventional Mixing vs EXAKT Milling

Compounding EXAKT

A comparative study conducted at the University of Hamburg, Institute of Pharmacy in Hamburg Germany concluded that the quality of compounds processed with EXAKT ointment mills is better than those processed with electric mixing systems.

  1. The particle size is smaller and the particle size distribution is more narrow.
  2. Ointment stability is better.
  3. Temperatures do not increase significantly during processing.
  4. Ointments are softer consistency with lower flow limits
  5. Three roll mills allow for quality control during processing.

Learn more.

Substance processed with conventional mixing procedure: crystalline substances are still clearly visible.

Substance processed with an EXAKT three roll mill: regular and fine consistency of the substance

The EXAKT 120S-450 Three Roll Mill

EXAKT-120S-Plus-hopper-pfa-scraper

The latest generation of the EXAK T 120S Plus Three Roll Mill technology features state-of-the-art safety functionality, optimum operation and precise setting of the gap.

The EXAKT 120S Plus offers continuously good results at particle fineness down to 5 μm. When the increased volume and simple handling are required, the 120S-450 is the best choice.  A continuously adjustable processing speed, excellent temperature control, and alternative roller materials provide the best prerequisites for a multitude of material requirements. The benchtop model is found everywhere in production. The solid processing of the machine provides absolutely parallel, manually adjusted roller gaps for uniform processing.

  • Easily monitor speed, temperature, production timer, and power consumption.
  • Gap range: 5 μm – 220 μm
  • Throughput: Up to 27.5 l/h with a gap width of 10 μm
  • Roller material: Chrome or aluminum oxide
  • State-of-the-art safety features
  • Mode for safe cleaning

Click here to see how EXAKT  mills work.

EXAKT-120S+-reverse-angle

7 Reasons to Choose the 80E Plus Mill

EXAKT80E Pus Hopper

The 80E PLUS three roll mill delivers faster-dispersing results with real-time process analysis. By combining high-precision mechanical design with a state-of-the-art electronic control system, EXAKT has created the new standard for three roll mill technology.

Users will have more information than ever before, and the ability to make adjustments on the go.

  1. Safe operation mode for the cleaning process
  2. Numeric or graphical real-time presentation of all relevant production parameters
  3. Easy to use data transfer via USB interface
  4. Gap Mode: Adjustable gap size from 5 to 180 μm
  5. Force Mode: Line pressure adjustable up to max. 26 N/mm, depending on the working width
  6. Variable throughput from as little as 10 ml up to 18 l/h at a 10 μm gap
  7. Roller materials chrome, tungsten carbide, aluminum oxide, or silicon carbide

Request quote.

 

Mixing vs. EXAKT Three Roll Mills

EXAKT Ointment Mill Results

A comparative study conducted at the University of Hamburg, Institute of Pharmacy in Hamburg, Germany concluded that the quality of compounds processed with three roll mills is better than those processed with electric mixing systems.

  1. The particle size is smaller and the particle size distribution is more narrow.
  2. Three roll mill stability is better.
  3. Temperatures do not increase significantly during processing.
  4. Ointments are softer consistency with lower flow limits
  5. Three roll mills allow for quality control during processing.

To see EXAKT three roll mill videos, click here.

Request quote. 

Substance processed with conventional mixing procedure: crystalline substances are still clearly visible.

Substance processed with an EXAKT three roll mill: regular and fine consistency of the substance